2013年6月22日星期六

Amyloid Nephropathy: Cause, Treatment, Symptoms

What is Amyloid Nephropathy?
Amyloid Nephropathy is characterized by numerous amyloid fibers depositing on the renal tissues. primary disease-amyloidosis. The amyloid fiber is a glass-like thing and includes amyloid protein, amyloid protein A, prealbumin, etc. amyloid fiber can be are the main cells that can be produced and decomposed by Macrophages.
What are Causes of Amyloid Nephropathy?
1. Complications.
Neoplastic disease, infectious disease and immunological disease are the main cause of Amyloid Nephropathy. About three quaters secondary amyloidosis may progress to Amyloid Nephropathy and the others are Amyloid Nephropathy.
2. Immune system.
In the condition of immune dysfunction, proteins are not able to be resolved as normal but collect in the tissues, forming amyloid fiber which is regarded as foreign invaders. Then inflammation will occur and kidney cells will be damaged, after some time, patients may have symptoms.
What are the Symptoms of Amyloid Nephropathy?
If the disease can not be treated well, Amyloid Nephropathy can aggravate into Kidney Failure at last. Hence, it is better for patents know the symptoms well.
1. Protein urine.
2. Swelling (edema) of the eyelids, the lower limbs and the whole body
3. Big tongue (amyloid macroglossia)
4. High blood pressure.
5. Hypoalbuminemia and hyperlipidaemia
6. Blood urine.
7. Pain in the abdomen, loin and back pain

8. Fatigue and some patients may have nausea.

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