2013年10月28日星期一

The Symptoms and Causes of Nephrotic Syndrome

Nephrotic syndrome is contributed by many causes. It is characterized by the increase of glomerular permeability. What are the symptoms and causes of nephritic syndrome?
Nephrotic syndrome has very obvious symptoms. Once you develop the following symptoms, you are more likely attacked by nephrotic syndrome.
u High level of protein in urine. (the proteinuria is greater than 3-3.5g/24hours.)
u Hypoalbuminemia
u Hyperlipidemia
u Edema
There are other symptoms that may indicate nephrotic syndrome.
u Hypercoagulability
u Hypertension
u Elevated serum creatinine level
u lipiduria
There are many causes of nephrotic syndrome
It can be caused by a wide range of primary (idiopathic) and secondary glomerular diseases.
Primary glomerular disease
Minimal-change glomerular disease (15%) - the most common cause in children.
Membranoproliferative glomerulonephritis (14%).
Focal segmental glomerulosclerosis (35% of nephrotic syndrome) - the most common cause of idiopathic nephrotic syndrome in adults.[5]
Membranous glomerular disease (33%).
Secondary glomerular disease
Infection, eg HIV, hepatitis B and hepatitis C, mycoplasma, syphilis, malaria,schistosomiasis, filariasis, toxoplasmosis
Inherited disease, eg Alport's syndrome, hereditary nephritis, sickle cell disease.
Malignant disease, eg multiple myeloma, leukaemia, lymphoma, carcinoma of breast,carcinoma of lung, carcinoma of colon and carcinoma of stomach.
Collagen vascular diseases, eg systemic lupus erythematosus, rheumatoid arthritis,polyarteritis nodosa, Henoch-Schönlein purpura, vasculitides.

Since you know the symptoms and the causes of nephrotic syndrome, you should take treatment as soon as possible if you have nephrotic syndrome. You can send an email to kidneyask@hotmail.com for the correct treatment.

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